If you are using sound to energize, clear, or balance the first chakra, the vibration and energy frequency using the note of "C" is the tone aligned with that chakra.
You may also use drums in a meditation, and those sounds and vibrations are more stimulating to the lower chakras; 1st, 2nd, and 3rd chakras.
In addition, chanting is another sound tool used in meditation, and chants are also used mostly to stimulate the chakras closer to the earth.
Music can also be used as a tool as well. It is often used for relaxation, or to change ones mood, and at times to help carry a persons thoughts to another realm.
The energy vibrations from sound can also be used as a means to heal. Sound has a way of helping to process different emotions and move Qi within the body. This not only can help clear the chakras, it can also be used to help with healing.
The spiritual development tool of sound can be used by anyone, but those who are very sensitive to music will be those become drawn to using this as their preferred spiritual development tool.